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Cell Res 29(6):460473 Acknowledgements We thank Biorender for providing high-quality image material for this study

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Several network meta-analyses have compared the efficacy of different GLP-1RAs.1718192021 However, the development of GLP-1RA novel drugs is indeed a rapidly evolving area, and many new drugs have emerged this year, including orforglipron, retatrutide, and CagriSema (semaglutide with cagrilintide)

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Use these as a temporary measure and try to rely more on dietary changes and supplements for long-term relief

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